P11R (p.Pro11Arg) variant of LRP5 (O75197)
P11R (p.Pro11Arg) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
P11R (p.Pro11Arg) variant details
- p.Pro11Arg
- gnomAD 11-68312746-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.444
- REVEL 0.33
- CADD 5.86
- PolyPhen-2 0.88
- SIFT 0.53
- Population evidence available
- Structural context available
- Literature evidence available