P11Q (p.Pro11Gln) variant of LRP5 (O75197)
P11Q (p.Pro11Gln) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
P11Q (p.Pro11Gln) variant details
- p.Pro11Gln
- gnomAD 11-68312746-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- REVEL 0.34
- CADD 6.12
- PolyPhen-2 0.88
- SIFT 0.44
- Population evidence available
- Structural context available
- Literature evidence available