P11A (p.Pro11Ala) variant of LRP5 (O75197)
P11A (p.Pro11Ala) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
P11A (p.Pro11Ala) variant details
- p.Pro11Ala
- gnomAD 11-68312745-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.29
- CADD 4.02
- PolyPhen-2 0.54
- SIFT 0.75
- Population evidence available
- Structural context available
- Literature evidence available