L22L (p.Leu22Leu) variant of LRP5 (O75197)
L22L (p.Leu22Leu) in LRP5 (O75197) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
L22L (p.Leu22Leu) variant details
- p.Leu22Leu
- gnomAD 11-68312778-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.277
- CADD 8.30
- Most common in the South Asian population (allele frequency 9.5e-05)
- Structural context available
- Literature evidence available