L19M (p.Leu19Met) variant of LRP5 (O75197)
L19M (p.Leu19Met) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
L19M (p.Leu19Met) variant details
- p.Leu19Met
- gnomAD 11-68312769-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.33
- CADD 14.50
- PolyPhen-2 0.67
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available