L18L (p.Leu18Leu) variant of LRP5 (O75197)
L18L (p.Leu18Leu) in LRP5 (O75197) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
L18L (p.Leu18Leu) variant details
- p.Leu18Leu
- rs777352225
- gnomAD 11-68312766-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.145
- CADD 9.05
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available
- Literature evidence available