L16M (p.Leu16Met) variant of LRP5 (O75197)
L16M (p.Leu16Met) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
L16M (p.Leu16Met) variant details
- p.Leu16Met
- gnomAD 11-68312760-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.21
- CADD 9.68
- PolyPhen-2 0.00
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available