L15P (p.Leu15Pro) variant of LRP5 (O75197)
L15P (p.Leu15Pro) in LRP5 (O75197) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
L15P (p.Leu15Pro) variant details
- p.Leu15Pro
- gnomAD 11-68312757-CTG-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.452
- CADD 20.70
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available