L15M (p.Leu15Met) variant of LRP5 (O75197)
L15M (p.Leu15Met) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L15M (p.Leu15Met) variant details
- p.Leu15Met
- gnomAD 11-68312757-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.23
- CADD 5.12
- PolyPhen-2 0.00
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available