L15A (p.Leu15Ala) variant of LRP5 (O75197)
L15A (p.Leu15Ala) in LRP5 (O75197) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
L15A (p.Leu15Ala) variant details
- p.Leu15Ala
- gnomAD 11-68312755-TGC-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.655
- CADD 21.40
- Population evidence available
- Structural context available
- Literature evidence available