L12L (p.Leu12Leu) variant of LRP5 (O75197)
L12L (p.Leu12Leu) in LRP5 (O75197) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
L12L (p.Leu12Leu) variant details
- p.Leu12Leu
- gnomAD 11-68312748-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.128
- CADD 6.65
- Most common in the East Asian population (allele frequency 0.00025)
- Structural context available
- Literature evidence available