G24S (p.Gly24Ser) variant of LRP5 (O75197)
G24S (p.Gly24Ser) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
G24S (p.Gly24Ser) variant details
- p.Gly24Ser
- ExAC rs746511983
- TOPMed rs746511983
- gnomAD rs746511983
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.22
- CADD 12.70
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 2.4e-06)
- Structural context available