G24R (p.Gly24Arg) variant of LRP5 (O75197)
G24R (p.Gly24Arg) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
G24R (p.Gly24Arg) variant details
- p.Gly24Arg
- gnomAD 11-68312784-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.24
- CADD 13.20
- PolyPhen-2 0.00
- SIFT 0.35
- Most common in the REMAINING population (allele frequency 3.1e-05)
- Structural context available
- Literature evidence available