C306Y (p.Cys306Tyr) variant of LRP5 (O75197)

C306Y (p.Cys306Tyr) in LRP5 (O75197) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely pathogenic in the context of Exudative vitreoretinopathy 4. The available variant effect predictions contribute to a CATVariant prioritization score of 0.93 / 1. The record also includes structural context.

C306Y (p.Cys306Tyr) variant details