A21V (p.Ala21Val) variant of LRP5 (O75197)
A21V (p.Ala21Val) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A21V (p.Ala21Val) variant details
- p.Ala21Val
- gnomAD rs1419301372
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.17
- CADD 5.07
- PolyPhen-2 0.00
- SIFT 0.51
- Most common in the Latino/Admixed American population (allele frequency 0.00022)
- Structural context available