A21S (p.Ala21Ser) variant of LRP5 (O75197)
A21S (p.Ala21Ser) in LRP5 (O75197) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
A21S (p.Ala21Ser) variant details
- p.Ala21Ser
- gnomAD 11-68312775-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.17
- CADD 9.58
- PolyPhen-2 0.00
- SIFT 0.44
- Population evidence available
- Structural context available
- Literature evidence available