R146C (p.Arg146Cys) variant of LRP4 (O75096)

R146C (p.Arg146Cys) in LRP4 (O75096) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Congenital myasthenic syndrome 17; Cenani-Lenz syndactyly syndrome; Sclerosteosi. The record also includes structural context.

R146C (p.Arg146Cys) variant details