D95N (p.Asp95Asn) variant of LRP4 (O75096)
D95N (p.Asp95Asn) in LRP4 (O75096) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
D95N (p.Asp95Asn) variant details
- p.Asp95Asn
- rs1431228331
- gnomAD rs1431228331
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.13
- CADD 13.40
- PolyPhen-2 0.02
- SIFT 0.17
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available