W45R (p.Trp45Arg) variant of LRP2 (P98164)
W45R (p.Trp45Arg) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
W45R (p.Trp45Arg) variant details
- p.Trp45Arg
- gnomAD rs1453272607
- Missense
- Variant Prioritization Score for Impact Estimate 0.627
- CADD 24.90
- PolyPhen-2 0.79
- SIFT 0.00
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available