V86G (p.Val86Gly) variant of LRP2 (P98164)
V86G (p.Val86Gly) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
V86G (p.Val86Gly) variant details
- p.Val86Gly
- ExAC rs777608905
- gnomAD rs777608905
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- CADD 24.90
- PolyPhen-2 0.88
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available