T66A (p.Thr66Ala) variant of LRP2 (P98164)
T66A (p.Thr66Ala) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
T66A (p.Thr66Ala) variant details
- p.Thr66Ala
- gnomAD rs1213030084
- Missense
- Variant Prioritization Score for Impact Estimate 0.11
- CADD 5.70
- PolyPhen-2 0.17
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available