T11M (p.Thr11Met) variant of LRP2 (P98164)
T11M (p.Thr11Met) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
T11M (p.Thr11Met) variant details
- p.Thr11Met
- gnomAD rs1266874181
- Missense
- Variant Prioritization Score for Impact Estimate 0.728
- CADD 15.50
- PolyPhen-2 0.01
- SIFT 0.37
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available