T114P (p.Thr114Pro) variant of LRP2 (P98164)
T114P (p.Thr114Pro) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
T114P (p.Thr114Pro) variant details
- p.Thr114Pro
- gnomAD rs1559067605
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- CADD 18.00
- PolyPhen-2 0.42
- SIFT 0.04
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available