S24R (p.Ser24Arg) variant of LRP2 (P98164)
S24R (p.Ser24Arg) in LRP2 (P98164) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
S24R (p.Ser24Arg) variant details
- p.Ser24Arg
- ExAC rs770065910
- gnomAD rs770065910
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.134
- CADD 9.13
- PolyPhen-2 0.00
- SIFT 0.49
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available