S110T (p.Ser110Thr) variant of LRP2 (P98164)
S110T (p.Ser110Thr) in LRP2 (P98164) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes structural context.
S110T (p.Ser110Thr) variant details
- p.Ser110Thr
- rs768641585
- ClinGen CA59955878
- ClinVar RCV002010126
- Ensembl rs768641585
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.628
- AlphaMissense 0.10
- MetaLR 0.86
- MetaSVM 0.47
- PolyPhen-2 0.18
- SIFT 0.33
- MutPred 0.31
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available