R3P (p.Arg3Pro) variant of LRP2 (P98164)
R3P (p.Arg3Pro) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
R3P (p.Arg3Pro) variant details
- p.Arg3Pro
- TOPMed rs1172501525
- gnomAD rs1172501525
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- CADD 22.40
- PolyPhen-2 0.41
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available