R3H (p.Arg3His) variant of LRP2 (P98164)
R3H (p.Arg3His) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R3H (p.Arg3His) variant details
- p.Arg3His
- TOPMed rs1172501525
- gnomAD rs1172501525
- Missense
- Variant Prioritization Score for Impact Estimate 0.41
- CADD 23.30
- PolyPhen-2 0.55
- SIFT 0.03
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available