R126G (p.Arg126Gly) variant of LRP2 (P98164)
R126G (p.Arg126Gly) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
R126G (p.Arg126Gly) variant details
- p.Arg126Gly
- ExAC rs753886411
- gnomAD rs753886411
- Missense
- Variant Prioritization Score for Impact Estimate 0.663
- CADD 24.50
- PolyPhen-2 0.70
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available