L20Q (p.Leu20Gln) variant of LRP2 (P98164)
L20Q (p.Leu20Gln) in LRP2 (P98164) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
L20Q (p.Leu20Gln) variant details
- p.Leu20Gln
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.616
- CADD 16.70
- PolyPhen-2 0.37
- SIFT 0.16
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available