H111R (p.His111Arg) variant of LRP2 (P98164)
H111R (p.His111Arg) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
H111R (p.His111Arg) variant details
- p.His111Arg
- ExAC rs773221527
- gnomAD rs773221527
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- CADD 9.77
- PolyPhen-2 0.00
- SIFT 0.63
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available