G61D (p.Gly61Asp) variant of LRP2 (P98164)
G61D (p.Gly61Asp) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
G61D (p.Gly61Asp) variant details
- p.Gly61Asp
- TOPMed rs925936001
- gnomAD rs925936001
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- CADD 7.54
- PolyPhen-2 0.13
- SIFT 0.40
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available