G61A (p.Gly61Ala) variant of LRP2 (P98164)
G61A (p.Gly61Ala) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G61A (p.Gly61Ala) variant details
- p.Gly61Ala
- TOPMed rs925936001
- gnomAD rs925936001
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- CADD 15.20
- PolyPhen-2 0.91
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available