D90Y (p.Asp90Tyr) variant of LRP2 (P98164)
D90Y (p.Asp90Tyr) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
D90Y (p.Asp90Tyr) variant details
- p.Asp90Tyr
- TOPMed rs1684835252
- Missense
- Variant Prioritization Score for Impact Estimate 0.758
- CADD 23.80
- PolyPhen-2 0.88
- SIFT 0.15
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available