D128N (p.Asp128Asn) variant of LRP2 (P98164)
D128N (p.Asp128Asn) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
D128N (p.Asp128Asn) variant details
- p.Asp128Asn
- cosmic curated COSV55544
- ExAC rs756312774
- TOPMed rs756312774
- gnomAD rs756312774
- Missense
- Variant Prioritization Score for Impact Estimate 0.768
- CADD 23.90
- PolyPhen-2 0.98
- SIFT 0.07
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available