D102Y (p.Asp102Tyr) variant of LRP2 (P98164)
D102Y (p.Asp102Tyr) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
D102Y (p.Asp102Tyr) variant details
- p.Asp102Tyr
- cosmic curated COSV99790
- TOPMed rs1212764557
- gnomAD rs1212764557
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- CADD 9.44
- PolyPhen-2 0.07
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available