C74F (p.Cys74Phe) variant of LRP2 (P98164)
C74F (p.Cys74Phe) in LRP2 (P98164) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
C74F (p.Cys74Phe) variant details
- p.Cys74Phe
- cosmic curated COSV99791
- gnomAD rs1260276729
- Missense
- Variant Prioritization Score for Impact Estimate 0.655
- CADD 23.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available