G21R (p.Gly21Arg) variant of LRBA (P50851)
G21R (p.Gly21Arg) in LRBA (P50851) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data.
G21R (p.Gly21Arg) variant details
- p.Gly21Arg
- ExAC rs778080354
- gnomAD rs778080354
- Missense
- Variant Prioritization Score for Impact Estimate 0.487
- MetaLR 0.19
- MetaSVM -0.89
- CADD 23.30
- PolyPhen-2 0.25
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)