S26T (p.Ser26Thr) variant of LIPC (Hepatic triacylglycerol lipase)
S26T (p.Ser26Thr) in LIPC (Hepatic triacylglycerol lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
S26T (p.Ser26Thr) variant details
- p.Ser26Thr
- gnomAD 15-58432109-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.18
- CADD 19.80
- PolyPhen-2 0.23
- SIFT 0.34
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available