R65G (p.Arg65Gly) variant of LIPC (Hepatic triacylglycerol lipase)
R65G (p.Arg65Gly) in LIPC (Hepatic triacylglycerol lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
R65G (p.Arg65Gly) variant details
- p.Arg65Gly
- gnomAD 15-58538437-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.308
- REVEL 0.17
- MetaLR 0.58
- MetaSVM -0.58
- CADD 9.93
- PolyPhen-2 0.01
- SIFT 0.51
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available