L72S (p.Leu72Ser) variant of LIPC (Hepatic triacylglycerol lipase)
L72S (p.Leu72Ser) in LIPC (Hepatic triacylglycerol lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
L72S (p.Leu72Ser) variant details
- p.Leu72Ser
- TOPMed rs1419695477
- Missense
- Variant Prioritization Score for Impact Estimate 0.66
- REVEL 0.68
- CADD 24.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available