L45M (p.Leu45Met) variant of LIPC (Hepatic triacylglycerol lipase)
L45M (p.Leu45Met) in LIPC (Hepatic triacylglycerol lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
L45M (p.Leu45Met) variant details
- p.Leu45Met
- gnomAD 15-58538377-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.34
- MetaLR 0.70
- MetaSVM -0.08
- CADD 5.17
- PolyPhen-2 0.62
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available