K49T (p.Lys49Thr) variant of LIPC (Hepatic triacylglycerol lipase)
K49T (p.Lys49Thr) in LIPC (Hepatic triacylglycerol lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
K49T (p.Lys49Thr) variant details
- p.Lys49Thr
- gnomAD rs1263031616
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.23
- CADD 8.79
- PolyPhen-2 0.19
- SIFT 0.18
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available