G61S (p.Gly61Ser) variant of LIPC (Hepatic triacylglycerol lipase)
G61S (p.Gly61Ser) in LIPC (Hepatic triacylglycerol lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
G61S (p.Gly61Ser) variant details
- p.Gly61Ser
- gnomAD 15-58538425-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.406
- REVEL 0.29
- MetaLR 0.61
- MetaSVM -0.13
- CADD 17.90
- PolyPhen-2 0.11
- SIFT 0.37
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available