F8L (p.Phe8Leu) variant of LIPC (Hepatic triacylglycerol lipase)
F8L (p.Phe8Leu) in LIPC (Hepatic triacylglycerol lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
F8L (p.Phe8Leu) variant details
- p.Phe8Leu
- Ensembl rs1893141723
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.14
- CADD 5.35
- PolyPhen-2 0.00
- SIFT 0.26
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available