F55S (p.Phe55Ser) variant of LIPC (Hepatic triacylglycerol lipase)
F55S (p.Phe55Ser) in LIPC (Hepatic triacylglycerol lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
F55S (p.Phe55Ser) variant details
- p.Phe55Ser
- gnomAD 15-58538408-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.585
- REVEL 0.60
- MetaLR 0.79
- MetaSVM 0.58
- CADD 25.30
- PolyPhen-2 0.96
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available