E74D (p.Glu74Asp) variant of LIPC (Hepatic triacylglycerol lipase)
E74D (p.Glu74Asp) in LIPC (Hepatic triacylglycerol lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
E74D (p.Glu74Asp) variant details
- p.Glu74Asp
- ESP rs372176025
- TOPMed rs372176025
- gnomAD rs372176025
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.11
- CADD 13.90
- PolyPhen-2 0.19
- SIFT 0.54
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available