D2Y (p.Asp2Tyr) variant of LIPC (Hepatic triacylglycerol lipase)
D2Y (p.Asp2Tyr) in LIPC (Hepatic triacylglycerol lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
D2Y (p.Asp2Tyr) variant details
- p.Asp2Tyr
- ExAC rs756169441
- TOPMed rs756169441
- gnomAD rs756169441
- Missense
- Variant Prioritization Score for Impact Estimate 0.415
- REVEL 0.40
- CADD 23.10
- PolyPhen-2 0.14
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 2.8e-05)
- Structural context available