V37L (p.Val37Leu) variant of LHCGR (P22888)
V37L (p.Val37Leu) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
V37L (p.Val37Leu) variant details
- p.Val37Leu
- TOPMed rs1670170905
- Missense
- Variant Prioritization Score for Impact Estimate 0.179
- REVEL 0.13
- CADD 14.30
- PolyPhen-2 0.01
- SIFT 0.73
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available