T52S (p.Thr52Ser) variant of LHCGR (P22888)
T52S (p.Thr52Ser) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
T52S (p.Thr52Ser) variant details
- p.Thr52Ser
- TOPMed rs1385543959
- gnomAD rs1385543959
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.21
- CADD 6.79
- PolyPhen-2 0.01
- SIFT 0.52
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available