T108I (p.Thr108Ile) variant of LHCGR (P22888)
T108I (p.Thr108Ile) in LHCGR (P22888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
T108I (p.Thr108Ile) variant details
- p.Thr108Ile
- ESP rs145919704
- TOPMed rs145919704
- Missense
- Variant Prioritization Score for Impact Estimate 0.568
- REVEL 0.54
- CADD 23.80
- PolyPhen-2 1.00
- SIFT 0.26
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available